3-Hydroxyvaleric acid

3-Hydroxyvaleric acid is a five-carbon ketone body byproduct that can undergo an anaplerotic reaction to replenish the intermediates of the tricarboxylic acid cycle. 3-Hydroxyvaleric acid is one of the important monomers for the synthesis of polyhydroxyalkanoates (PHA) . PHA is a type of biodegradable plastic that is widely used in environmentally friendly packaging, disposable products, and medical materials[1].

Product Specifications

CAS Number

[10237-77-1]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/3-Hydroxyvaleric_acid.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CCC(O)CC(O)=O

Molecular Formula

C5H10O3

Molecular Weight

118.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Kallem RR, et al. Development and validation of a LC-MS/MS method for quantitation of 3-hydroxypentanoic acid and 3-oxopentanoic acid in human plasma and its application to a clinical study of glucose transporter type I deficiency (G1D) syndrome. J Pharm Biomed Anal. 2021 Oct 25;205:114335.|[2]Williams D R, et al. Production of a co-polyester of 3-hydroxybutyric acid and 3-hydroxyvaleric acid from succinic acid by Rhodococcus ruber: biosynthetic considerations[J]. Applied microbiology and biotechnology, 1994, 40: 717-723.