Trisdecanoin

Trisdecanoin (Tricaprin; Glyceryl tridecanoate) is an orally available precursor of decanoic acid (DA precursor) that can be hydrolyzed to decanoic acid. Trisdecanoin and its metabolite capric acid not only provide the body with a quick source of energy, but can also affect lipid metabolism. Trisdecanoin is a major component of medium chain triglycerides (MCT), which has preventive or inhibitory properties for abdominal aortic aneurysms (AAA), inhibition of cardiovascular disease, and anti-androgen (NSAA) and anti-hyperglycemic properties. Trisdecanoin can be used as an additive in food, medicine and cosmetics[1][2][3].

Product Specifications

CAS Number

[621-71-6]

Product Name Alternative

Tricaprin; Glyceryl tridecanoate

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Androgen Receptor; Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/trisdecanoin.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCC(OCC(COC(CCCCCCCCC)=O)OC(CCCCCCCCC)=O)=O

Molecular Formula

C33H62O6

Molecular Weight

554.84

Precautions

H302, H315, H319, H335

References & Citations

[1]Tricaprin (Code C153424) |[2]Suzuki A, et al. Tricaprin Rescues Myocardial Abnormality in a Mouse Model of Triglyceride Deposit Cardiomyovasculopathy. J Oleo Sci. 2018;67 (8) :983-989.|[3]Kugo H, et al. Tricaprin can prevent the development of AAA by attenuating aortic degeneration. Biomed Pharmacother. 2023;160:114299.