Bizine di(hydrochloride)
Product Specifications
UNSPSC Description
Bizine dihydrochloride, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine dihydrochloride can modulate bulk histone methylation in cancer cells. Bizine dihydrochloride shows neuroprotective effects[1].
Target Antigen
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bizine-di-hydrochloride.html
Smiles
O=C(NC1=CC=C(CCNN)C=C1)CCCC2=CC=CC=C2.Cl.Cl
Molecular Weight
370.32
References & Citations
[1]Prusevich P, et, al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20;9(6):1284-93.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121095A/Bizine-di-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121095A/
Clinical Information
No Development Reported
CAS Number
1808112-57-3
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