Clopimozide
Clopimozide is an orally active antischizophrenic agent that inhibits [3H]nitrendipine binding with IC50 value of 17 nM. Clopimozide is a calcium channel antagonist. Clopimozide can be used for the research of negative and positive schizophrenic symptoms[1].
Product Specifications
CAS Number
[53179-12-7]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/clopimozide.html
Purity
99.63
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1NC2=CC(Cl)=CC=C2N1C3CCN(CC3)CCCC(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F
Molecular Formula
C28H28ClF2N3O
Molecular Weight
495.99
References & Citations
[1]Gould RJ, et al. Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists. Proc Natl Acad Sci U S A. 1983 Aug;80 (16) :5122-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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