BVDV-IN-1

BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC) [1].

Product Specifications

CAS Number

[345651-04-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Flavivirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bvdv-in-1.html

Concentration

10mM

Purity

98.51

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OCCN1CCN(C2=C3C=CC=CC3=NC(C4=CC=CC=C4)=N2)CC1

Molecular Formula

C20H22N4O

Molecular Weight

334.41

Precautions

H302, H315, H319

References & Citations

[1]Gabriela A Fernández, et al. Design and Optimization of Quinazoline Derivatives: New Non-nucleoside Inhibitors of Bovine Viral Diarrhea Virus. Front Chem. 2020 Dec 10;8:590235.