AM4299B
Product Specifications
UNSPSC Description
AM4299B is an inhibitor for thiol protease. AM4299B inhibits bovine spleen cathepsin B, human kidney cathepsin L and papain with IC50s of 0.7, 0.5 and 20 μM, respectively. AM4299B can be used in research in osteoporosis, and has potential to be used as an antiparasitic agent[1].
Target Antigen
Cathepsin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/am4299b.html
Smiles
N[C@@H](CCCCNC([C@H](CC(C)C)NC(C1OC1C(O)=O)=O)=O)C(O)=O
Molecular Weight
373.40
References & Citations
[1]Morishita A, et al., AM4299 A and B, novel thiol protease inhibitors. J Antibiot (Tokyo). 1994 Sep;47(9):1065-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-120288/AM4299B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-120288/
Clinical Information
No Development Reported
CAS Number
160825-49-0
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