Menthone

Menthone, an orally active monoterpene that can be isolated from plants and Mentha oil with antibacterial, antitumor, antioxidation, and antivirus properties. Menthone is a main volatile component of the essential oil, and has anti-Inflammatory properties in Schistosoma mansoni infection and rheumatoid arthritis[1][2].

Product Specifications

CAS Number

[10458-14-7]

UNSPSC

12352211

Hazard Statement

H302, H319, H334, H412

Target

NF-κB; Parasite

Type

Natural Products

Related Pathways

Anti-infection; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/menthone.html

Concentration

10mM

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(C(C)C)CCC(C)C1

Molecular Formula

C10H18O

Molecular Weight

154.25

Precautions

H302, H319, H334, H412

References & Citations

[1]Mauricio G Zaia, et al. Anti-Inflammatory Properties of Menthol and Menthone in Schistosoma mansoni Infection. Front Pharmacol. 2016 Jun 17;7:170.|[2]Chen X, et al. A Natural Plant Ingredient, Menthone, Regulates T Cell Subtypes and Lowers Pro-inflammatory Cytokines of Rheumatoid Arthritis. J Nat Prod. 2022 Apr 22;85 (4) :1109-1117. |[3]Su YH, et al. Menthone supplementation protects from allergic inflammation in the lungs of asthmatic mice. Eur J Pharmacol. 2022 Sep 15;931:175222.|[4]Chen X, et al. Menthone inhibits type-I interferon signaling by promoting Tyk2 ubiquitination to relieve local inflammation of rheumatoid arthritis. Int Immunopharmacol. 2022 Nov;112:109228.