Succinamic acid
Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC50 of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336) [1][2].
Product Specifications
CAS Number
[638-32-4]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/succinamic-acid.html
Purity
97.0
Smiles
O=C(O)CCC(N)=O
Molecular Formula
C4H7NO3
Molecular Weight
117.10
Precautions
H315, H319, H335
References & Citations
[1]Carbone V, et al., Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Bioorg Med Chem. 2005 Jan 17;13 (2) :301-12.|[2]Chen Q, et al., A Prostate-Specific Membrane Antigen-Targeting Small Molecule-Drug Conjugate Strategy to Overcome the Hematological Toxicity of Olaparib. J Med Chem. 2024 Nov 14;67 (21) :19586-19611.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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