RDR 03785

RDR 03785 is a covalent MIF inhibitor with an IC50 of 0.36 μM[1].

Product Specifications

CAS Number

[289657-30-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Macrophage migration inhibitory factor (MIF)

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rdr-03785.html

Purity

97.05

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

OC1=CC2=C(OCO2)C=C1C(N3CCOCC3)C4=CC=C(C(F)(F)F)C=C4

Molecular Formula

C19H18F3NO4

Molecular Weight

381.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Cisneros JA, et al. Irregularities in enzyme assays: The case of macrophage migration inhibitory factor. Bioorg Med Chem Lett. 2016 Jun 15;26 (12) :2764-2767.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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