Luteolinidin (chloride)
Luteolinidin chloride is a deoxyanthocyanidin isolated from the plant Sorghum bicolor with antioxidant activity. Luteolinidin chloride is a potent CD38 inhibitor (Ki=11.4 μM) and protects the heart from ischemia/reperfusion injury by preserving endothelial nitric oxide synthase (eNOS) function and preventing endothelial dysfunction. Luteolinidin chloride is also a competitive inhibitor of tyrosinase (IC50=3.7 μM) and blocks the production of melanin[1][2][3][4][5].
Product Specifications
UNSPSC
12352005
Target
CD38; NADPH Oxidase; Tyrosinase
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/luteolinidin-chloride.html
Purity
99.73
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC2=[O+]C(C3=CC=C(O)C(O)=C3)=CC=C2C(O)=C1.[Cl-]
Molecular Formula
C15H11ClO5
Molecular Weight
306.70
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129997/Luteolinidin-chloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129997/Luteolinidin-chloride-SDS-MedChemExpress.pdf
Scientific Category
Natural Products
Clinical Information
No Development Reported
CAS Number
[1154-78-5]
Available Sizes
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