(Rac)-AF710B
Product Specifications
UNSPSC Description
(Rac)-AF710B is the racemate of AF710B (HY-116586). AF710B is a highly potent and selective allosteric M1 muscarinic and σ1 receptor agonist. AF710B can be used for the research of Alzheimer’s disease[1].
Target Antigen
mAChR; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-af710b.html
Smiles
O=C(CCC1=CNC2=C1C=CC=C2)N3CC4(CCN(CC4)C)SC3C
Molecular Weight
357.51
References & Citations
[1]Fisher A, et al. AF710B, a Novel M1/σ1 Agonist with Therapeutic Efficacy in Animal Models of Alzheimer’s Disease. Neurodegener Dis. 2016;16(1-2):95-110.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116586A/Rac-AF710B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116586A/
Clinical Information
No Development Reported
CAS Number
1235733-73-9
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