Cynomolgus Glypican 3 / GPC3 Protein, His Tag
Cynomolgus Glypican 3, His Tag (GP3-C5225) is expressed from human 293 cells (HEK293) . It contains AA Gln 25 - Arg 358 & Ser 359 - His 559 (Accession # XP_005594665.1) .
Product Specifications
Background
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.1 kDa & 24.6 kDa. The protein migrates as 42 kDa and 66-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
XP_005594665.1
Expression Region
Gln 25 - Arg 358 & Ser 359 - His 559
Host
HEK293
Target
Glypican 3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Cynomolgus
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
85%
Bioactivity
Immobilized Cynomolgus Glypican 3, His Tag (Cat. No. GP3-C5225) at 0.5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human GPC3 Antibody, Human IgG1 with a linear range of 0.2-3 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
38.1 kDa & 24.6 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
250ug*4
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/GP3-C5225.pdf
Species
Cynomolgus
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