Naxitamab
Product Specifications
UNSPSC Description
Naxitamab (Hu3F8) is a humanized monoclonal antibody targeting the disialoganglioside GD2. Naxitamab can be used in research of neuroblastoma, osteosarcoma and other GD2-positive cancers[1].
Target Antigen
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/naxitamab.html
Purity
98.13
Solubility
10 mM in DMSO
Smiles
[Naxitamab]
References & Citations
[1]Cheung NK, et, al. Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo. Oncoimmunology. 2012 Jul 1;1(4):477-486.|[2]Markham A. Naxitamab: First Approval. Drugs. 2021 Feb;81(2):291-296.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99206/Naxitamab-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99206/Naxitamab-SDS-MedChemExpress.pdf
Clinical Information
Phase 4
CAS Number
1879925-92-4
Available Sizes
Curated Selection
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