MS39N
Product Specifications
UNSPSC Description
MS39N (compound 27) is a negative control for MS39 that binds EGFR without inducing degradation[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Field of Research
others
Assay Protocol
https://www.medchemexpress.com/ms39n.html
Solubility
10 mM in DMSO
Smiles
COC(C(OCCCN1CCN(CC1)C(CCCCCCCCCC(N[C@@H](C(C)(C)C)C(N2[C@H](C[C@@H](C2)O)C(NCC3=CC=C(C4=C(C)N=CS4)C=C3)=O)=O)=O)=O)=C5)=CC6=C5C(NC7=CC(Cl)=C(C=C7)F)=NC=N6
Molecular Weight
1056.72
References & Citations
[1]Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-molecule Degraders. J Med Chem. 2020 Feb 13;63(3):1216-1232.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157582/MS39N-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157582/
Clinical Information
No Development Reported
CAS Number
2675490-96-5
Curated Selection
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