Vanillylmandelic acid-d3
Product Specifications
Product Name Alternative
Mutagenic Impurity of Tenofovir Disoproxil; Tenofovir Impurity 2,(Z)-Mutagenic Impurity of Tenofovir Disoproxil
UNSPSC Description
Vanillylmandelic acid-d3 is the deuterium labeled Vanillylmandelic acid. Vanillylmandelic acid is the endproduct of epinephrine and norepinephrine metabolism. Vanillylmandelic acid can be used as an indication of the disorder in neurotransmitter metabolism as well. Vanillylmandelic acid has antioxidant activity towards DPPH radical with an IC50 value of 33 μM[1].
Target Antigen
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C(C1=CC(OC([2H])([2H])[2H])=C(C=C1)O)O)=O
Molecular Weight
201.192
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Michalis K Kolentinis, et al.Cardiovascular effects of vanillylmandelic acid in rats. Eur J Pharmacol. 2013 Mar 5;703(1-3):46-52.|[3]Dušan Dimić, et al. Experimental and theoretical elucidation of structural and antioxidant properties of vanillylmandelic acid and its carboxylate anion. Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jun 5;198:61-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
74495-70-8
Available Sizes
Curated Selection
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