JNJ-63576253 (TRC-253)
Product Specifications
CAS Number
2110428-64-1
SKU
C18284-25mg
Target
Androgen Receptor
Applications
Endocrinology & Hormones
Smiles
Cl.FC (F) (F) C1=CC (=CN=C1C#N) N2C (=O) C3 (CCC3) N (C2=S) C4=CN=C (OC5CCNCC5) C=C4
Molecular Formula
C23H22ClF3N6O2S
Additionnal Information
JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.
Storage Conditions
3 years -20°C powder
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