JNJ-63576253 (TRC-253)

Product Specifications

CAS Number

2110428-64-1

SKU

C18284-25mg

Target

Androgen Receptor

Applications

Endocrinology & Hormones

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Cl.FC (F) (F) C1=CC (=CN=C1C#N) N2C (=O) C3 (CCC3) N (C2=S) C4=CN=C (OC5CCNCC5) C=C4

Molecular Formula

C23H22ClF3N6O2S

Additionnal Information

JNJ-63576253 (TRC-253) is a potent and selective androgen receptor (AR) Antagonist with IC50 of 6.9 nM. JNJ-63576253 displays robust inhibition in WT and LBD-mutated, enzalutamide-resistant models of prostate cancer.

Storage Conditions

3 years -20°C powder

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