Prexasertib (LY2606368)
Product Specifications
CAS Number
1234015-52-1
Synonyms
ACR 368
SKU
C11847-5mg
Target
Chk
Applications
Cell Cycle
Smiles
COC1=C (C2=CC (=N[NH]2) NC3=CN=C (C=N3) C#N) C (=CC=C1) OCCCN
Molecular Formula
C18H19N7O2
Additionnal Information
Prexasertib (LY2606368, ACR 368) is a selective ATP competitor inhibitor of Chk1 and Chk2 with IC50s of 1 nM and 8 nM in cell-free assays, respectively. Prexasertib also inhibits RSK1 with an IC50 of 9 nM in cell-free assay.
Storage Conditions
3 years -20°C powder
Available Sizes
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