4'-Bromo-resveratrol
Product Specifications
Product Name Alternative
4′‐BR
UNSPSC Description
4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].
Target Antigen
Apoptosis; Sirtuin
Type
Reference compound
Related Pathways
Apoptosis;Cell Cycle/DNA Damage;Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/4-bromo-resveratrol.html
Purity
99.81
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OC1=CC(O)=CC(/C=C/C2=CC=C(C=C2)Br)=C1
Molecular Weight
291.144
References & Citations
[1]George J, et al. 4'-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. Mol Carcinog. 2019;58(10):1876-1885.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-124113/4-Bromo-resveratrol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-124113/4-Bromo-resveratrol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1224713-90-9
Available Sizes
Curated Selection
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