PTP1B-IN-2

Product Specifications

CAS Number

1919853-46-5

Synonyms

MDK3465, Ptp1B-In-2, Compound P6

SKU

C07012-5mg

Target

Phosphatase

Applications

Metabolism

Smiles

CC1=CC=C (C=C1) COC2=C (C=C (C=C2) N (CC3=CC=C (C=C3) N (CC (=O) OC) S (=O) (=O) C) S (=O) (=O) CC4=CC=CC=C4) C (=O) OC

Molecular Formula

C34H36N2O9S2

Additionnal Information

PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose uptake.