Androgen Receptor Mouse mAb IHC Kit
Product Specifications
Background
Androgen receptor (AR) is a member of the ligand response transcription regulator superfamily, which is expressed in prostate, testis and sweat gland. Upon AR binding the receptor, it stimulates androgen responsive genes transcription. AR plays an important role in the occurrence and development of prostate cancer. The higher the degree of differentiation of prostate cancer tissue, the higher the expression of AR, and the hormone treatment effect of positive prostate cancer patients is better. AR is mainly used for the detection of prostate cancer, guiding clinical treatment, and can also be used for other cancers such as esophageal cancer and breast cancer.
Synonyms
AIS, Androgen receptor, AR, AR8, DHTR, Dihydro testosterone receptor, Dihydrotestosterone receptor (DHTR), HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4 (NR3C4), Nuclear receptor subfamily 3 group C member 4, SBMA, SMAX1, Spinal and bulbar muscular atrophy (SBMA), Spinal and bulbar muscular atrophy, Testicular Feminization (TFM), TFM
Gene Name
AR
Gene ID
367
Swiss Prot
P10275
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide corresponding to the amino acid region 27 - 150 of the human Androgen Receptor protein.
Applications
Immunohistochemistry (IHC)
Dilution
It has been optimized for direct use, requiring no further dilution.
Specificity
The antibody can specifically recognize human AR protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Subcellular Location
Nuclear
Protein Name
Androgen Receptor
Available Sizes
Curated Selection
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