Thyroid transcription factor-1 (TTF1) (AB1688) Rabbit mAb (Ready to Use)
Product Specifications
Background
Thyroid transcription factor 1 (TTF- 1) is a nuclear protein with a molecular weight of 38- 40 kDa. It is the basic material for thyroid differentiation and the regulation of thyroglobulin secretion. It can promote the transport of thyroid peroxidase and iodine / sodium. TTF- 1 is mainly distributed in type II alveolar epithelium, respiratory epithelium and Clara cells of thyroid and lung in adult tissues, but it is not expressed in type I alveolar epithelium. It is mainly used for the diagnosis of small cell lung cancer, the differential diagnosis of primary lung adenocarcinoma from metastatic adenocarcinoma, and the differential diagnosis of lung cancer from malignant mesothelioma and paraganglioma of pleura.
Synonyms
AV026640; BCH; Benign chorea; BHC; Homeobox protein NK 2 homolog A; Homeobox protein NK-2 homolog A; Homeobox protein Nkx 2. 1; Homeobox protein Nkx-2. 1; Homeobox protein Nkx2. 1; NK 2; NK 2 homolog A; NK2; NK2 homeobox 1; NK2, drosophila, homolog of, A; NK2. 1, Mouse, homolog of; Nkx 2 1; NKX 2. 1; NKX 2A; NKX2 1; Nkx2-1; NKX2. 1; NKX21_HUMAN; NKX2A; T EBP; T/EBP; TEBP; Thyroid nuclear factor 1; Thyroid nuclear factor; Thyroid specific enhancer binding protein; Thyroid transcription factor 1; Tin man; Tinman; TITF 1; TITF1; TTF 1; TTF-1; TTF1
Gene Name
NKX2-1
Gene ID
7080
Swiss Prot
P43699
Host
Rabbit
Reactivity
Human; Mouse; (predicted: Rat)
Immunogen
A synthetic peptide corresponding to the amino acid region 50 - 150 of the human Thyroid transcription factor - 1 protein.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
IHC
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
It has been optimized for direct use, requiring no further dilution.
Modification
Unmodified
Storage Conditions
Store at 4°C. Avoid freeze.
Specificity
The antibody can specifically recognize human TTF1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Protein Name
Thyroid transcription factor-1
Available Sizes
Curated Selection
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