MDR1 (AB1689) Rabbit mAb (Ready to Use)
Product Specifications
Background
MDR- 1, also known as P- 170, is a membrane glycoprotein encoded by MDR gene. Its main function is to quickly pump cytotoxic drugs out of cells by ATP. Its expression level is related to the permeability of cell membrane, intracellular drug concentration and the degree of drug resistance. It is mainly used in the study of tumor drug resistance.
Synonyms
ABC20; ABCB1; ATP binding cassette, sub family B (MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1
Gene Name
ABCB1
Gene ID
5243
Swiss Prot
P08183
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
A synthetic peptide corresponding to the amino acid region 600 - 700 of the human MDR1 protein.
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
IHC
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
It has been optimized for direct use, requiring no further dilution.
Modification
Unmodified
Storage Conditions
Store at 4°C. Avoid freeze.
Specificity
The antibody can specifically recognize human MDR1 protein.
Formulation
The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05% Proclin 300.
Protein Name
MDR1
Available Sizes
Curated Selection
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