PAX-8 (AB1646) Rabbit mAb
Product Specifications
Background
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Synonyms
PAX8, Paired box protein Pax-8
Gene Name
PAX8
Gene ID
7849
Swiss Prot
Q06710
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the amino acid region 150 - 250 of the human PAX - 8 protein
Clonality
Monoclonal
Source
Monoclonal, Rabbit, IgG
Applications
IHC, ELISA
Purification
The antibody was purified by protein A affinity chromatography.
Dilution
IHC, 1:200-1:400 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Modification
Unmodified
Storage Conditions
Store at-20°C. Avoid freeze / thaw cycles.
Specificity
This antibody detects endogenous levels of PAX-8 protein.
Formulation
The antibody is provided in liquid form in phosphate - buffered saline with 50% glycerol, 0.05% BSA, and 0.05% Proclin 300.
Protein Name
PAX-8
Available Sizes
Curated Selection
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