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β-Caryophyllene-d2

Product Specifications

UNSPSC Description

β-Caryophyllene-d2 is deuterium labeled β-Caryophyllene. β-Caryophyllene is a CB2 receptor agonist.

Target Antigen

Cannabinoid Receptor; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Neurological Disease

Purity

94.22

Solubility

10 mM in DMSO

Smiles

CC1([C@@]2([H])[C@](/C(CC/C=C(CC2)/C)=C([2H])\[2H])([H])C1)C

Molecular Weight

206.36

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Cheng Y, et al. β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway. Pharmacology. 2014;94(1-2):1-12.|[3]Dahham SS, et al. The Anticancer, Antioxidant and Antimicrobial Properties of the Sesquiterpene β-Caryophyllenefrom the Essential Oil of Aquilaria crassna. Molecules. 2015 Jun 26;20(7):11808-29.|[4]de Oliveira CC, et al. Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures. Epilepsy Behav. 2016 Mar;56:26-31.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Clinical Information

No Development Reported

CAS Number

2006272-96-2

Available Sizes

Curated Selection

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