Pirodavir
Pirodavir is a potent, broad-spectrum picornavirus inhibitor, and is highly active against both group A and group B rhinovirus serotypes.Pirodavir is very potent in a virus yield reduction assay (IC90=2.3 nM) .
Product Specifications
CAS Number
[124436-59-5]
Product Name Alternative
R77975
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Enterovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Pirodavir.html
Purity
99.18
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C(OCC)C1=CC=C(OCCC2CCN(C3=NN=C(C)C=C3)CC2)C=C1
Molecular Formula
C21H27N3O3
Molecular Weight
369.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Barnard DL, et al. In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity. Antimicrob Agents Chemother. 2004 May;48 (5) :1766-72.|[2]Andries K, et al. In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviralactivity. Antimicrob Agents Chemother. 1992 Jan;36 (1) :100-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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