L-Ascorbic acid (GMP)

L-Ascorbic acid (L-Ascorbate) (GMP) is Ascorbic acid (HY-B0166) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Cav 3.2 channels[1].

Product Specifications

CAS Number

[50-81-7]

Product Name Alternative

L-Ascorbate (GMP) ; Vitamin C (GMP)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species (ROS)

Type

GMP Small Molecules

Related Pathways

Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-ascorbic-acid-gmp.html

Purity

99.2

Solubility

10 mM in DMSO

Smiles

OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O

Molecular Formula

C6H8O6

Molecular Weight

176.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Barlian A, et al. Chondrogenic differentiation of Wharton's Jelly mesenchymal stem cells on silk spidroin-fibroin mix scaffold supplemented with L-ascorbic acid and platelet rich plasma. Sci Rep. 2020 Nov 10;10 (1) :19449.|[2]Mekala NK, et al. Enhanced proliferation and osteogenic differentiation of human umbilical cord blood stem cells by L-ascorbic acid, in vitro. Curr Stem Cell Res Ther. 2013 Mar;8 (2) :156-62.