ZMC3
Product Specifications
UNSPSC Description
ZMC3 (NSC328784) is a zinc chelator. ZMC3 shows Zinc metallochaperone properties. ZMC3 shows enhanced sensitivity in p53-R175H mutant cells. ZMC3 increases the cell ROS level[1].
Target Antigen
Reactive Oxygen Species
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zmc3.html
Smiles
C/C(C1=NC=CC=C1)=N\NC(N2CCN(C3=NC=CC=C3)CC2)=[Se]
Molecular Weight
387.34
References & Citations
[1]Yu X, et al. Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53. Mol Pharmacol. 2017 Jun;91(6):567-575.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126905/ZMC3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126905/
Clinical Information
No Development Reported
CAS Number
79514-41-3
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