Gln-AMS
Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes.
Product Specifications
CAS Number
[209543-57-7]
UNSPSC
12352005
Target
Aminoacyl-tRNA Synthetase; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Gln-AMS.html
Purity
98.71
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCC(N)=O)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
Molecular Formula
C15H22N8O8S
Molecular Weight
474.45
References & Citations
[1]Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.|[2]Atta-ur-Rahman, et al. Frontiers in Natural Product Chemistry.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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