Anti-MRSA agent 14

Anti-MRSA agent 14 (Compound C17) has antibacterial agent against MRSA and MRSA-infected skin murine model. Anti-MRSA agent 14 is more potential than Norfloxacin (HY-B0132) against MRSA. Anti-MRSA agent 14 disrupts cell membrane and restrains metabolism. Anti-MRSA agent 14 shows antibacterial effects against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA with MIC values of 1, 2, 2, 1 μM respectively[1].

Product Specifications

CAS Number

[3050586-22-3]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/anti-mrsa-agent-14.html

Smiles

CC1(C)CC[C@]2(C(NS(C3=CC=C(Cl)C=C3)(=O)=O)=O)CC[C@@]4(C)[C@]5(C)CC[C@@]6([H])C(C)(C)C7=C(C(C=CC=C8C(O)=O)=C8N7)C[C@]6(C)[C@@]5([H])CC=C4[C@]2([H])C1

Molecular Formula

C43H53ClN2O5S

Molecular Weight

745.41

References & Citations

[1]Li J, et al. Design and synthesis of unique indole-benzosulfonamide oleanolic acid derivatives as potent antibacterial agents against MRSA. Eur J Med Chem. 2024 Jun 27;276:116625.