D-Tyrosine-d2
D-Tyrosine-d2 is the deuterium labeled D-Tyrosine (HY-Y0444) [1]. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth[2][3].
Product Specifications
CAS Number
[1202064-22-9]
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Tyrosinase
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
OC([C@H](N)C([2H])([2H])C1=CC=C(C=C1)O)=O
Molecular Formula
C9H9D2NO3
Molecular Weight
183.20
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Cong Yu, et al. Inhibition of Biofilm Formation by D-tyrosine: Effect of Bacterial Type and D-tyrosine Concentration. Water Res. 2016 Apr 1;92:173-9.|[3]Jisu Park, et al. D-tyrosine Negatively Regulates Melanin Synthesis by Competitively Inhibiting Tyrosinase Activity. Pigment Cell Melanoma Res. 2018 May;31 (3) :374-383.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-Y0444S/
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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