Senecionine N-oxide-d3
Product Specifications
UNSPSC Description
Senecionine N-oxide-d3 is the deuterium labeled Senecionine N-oxide. Senecionine n-oxide is the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Senecionine N-oxide has anti-cancer activity[1][2].
Target Antigen
Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
O=C(O[C@]1([H])CC[N+]2([O-])[C@]1([H])C(COC([C@@](O)(C([2H])([2H])[2H])[C@H](C)C/3)=O)=CC2)C3=C/C
Molecular Weight
354.41
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Thomas Hartmann, et al. Senecionine n-oxide, the primary product of pyrrolizidine alkaloid biosynthesis in root cultures of Senecio vulgaris. Phytochemistry, Volume 26, Issue 6, 1987, Pages 1639-1643|[3]Kupchan SM, et al. Tumor inhibitors. XXII. Senecionine and senecionine N-oxide, the active principles of Senecio triangularis. J Pharm Sci. 1967 Apr;56(4):541-3.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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