Bz-rA

Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway[1][2].

Product Specifications

CAS Number

[4546-55-8]

Product Name Alternative

N6-Benzoyladenosine

UNSPSC

12352005

Hazard Statement

H302

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bz-ra.html

Purity

99.51

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=NC3=C2N=CN=C3NC(C4=CC=CC=C4)=O

Molecular Formula

C17H17N5O5

Molecular Weight

371.35

Precautions

H302

References & Citations

[1]Shimada K, et al. Oxidative photocyclization of N6-benzoyladenosine derivatives. Facile formation of the quinazolinopurine ring system[J]. Tetrahedron letters, 1987, 28 (2) : 207-210.|[2]Aronoff DM, et al. Cutting edge: macrophage inhibition by cyclic AMP (cAMP) : differential roles of protein kinase A and exchange protein directly activated by cAMP-1. J Immunol. 2005 Jan 15;174 (2) :595-9.