CYD-2-88
CYD-2-88 (BDA-366 analog) is a BDA-366 (HY-101083) (Bcl2 BH4 antagonist) analog. CYD-2-88 (20 mg/kg, i.p.) inhibits tumor growth in NSCLC H460 xenografts mice[1].
Product Specifications
CAS Number
[1821496-27-8]
Product Name Alternative
BDA-366 analog
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyd-2-88.html
Smiles
O[C@@H](CNC1=CC=C(C2=C1C(C3=C(C=CC=C3)C2=O)=O)NC[C@@H]4OC4)CN5CCCCC5
Molecular Formula
C25H29N3O4
Molecular Weight
435.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Xingming DENG, et al. Bh4 antagonists and methods related thereto. Patent. WO2015171589.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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