M2 Peptide
Product Specifications
UNSPSC Description
M2 Peptide is a peptide targeting M2-like tumor-associated macrophages (TAMs). M2 Peptide is used to carry drugs or small interfering RNA (siRNA) to promote the repolarization of M2-like macrophages to M1-like macrophages, thereby altering the immunosuppressive state in the tumor microenvironment and enhancing the anti-tumor immune response. M2 Peptide can be used to study the effect of macrophage polarization and how this polarization change affects tumor growth and metastasis[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m2-peptide.html
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CC5=CNC6=CC=CC=C56)C(N7[C@@H](CCC7)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](CS)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC9=CC=C(C=C9)O)N
Molecular Weight
1758.95
References & Citations
[1]Xiao H, et al. M2-like tumor-associated macrophage-targeted codelivery of STAT6 inhibitor and IKKβ siRNA induces M2-to-M1 repolarization for cancer immunotherapy with low immune side effects[J]. ACS central science, 2020, 6(7): 1208-1222.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10449/M2-Peptide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10449/
Clinical Information
No Development Reported
Curated Selection
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