15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide
Product Specifications
UNSPSC Description
15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide (compound 2) is an enantio-kaurene diterpenoid (ent -kaurene diterpenoid), which can be isolated from Rubescens rubescens. 15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α(6,11α)-diolide has cellular activity against EC-1, U87, A549, MCF-7 and HeLa cell lines Toxicity, IC50s are 37.69 μM, 79.362 μM, 80.07 μM, 197.35 μM, 462.13 μM, and 180.09 μM respectively[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/15α-hydroxy-20-oxo-6-7-seco-ent-kaur-16-en-1-7α-6-11α-diolide.html
Solubility
10 mM in DMSO
Smiles
O=C[C@]([C@@]1([H])C2(C)C)([C@@](CC2)([H])OC3=O)[C@@]4([H])[C@]3([C@@H](C5=C)O)C[C@@]5([H])C[C@]4([H])OC1=O
Molecular Weight
360.40
References & Citations
[1]Xie RJ, et al. Two new diterpenoids and other constituents from Isodon rubescens. Fitoterapia. 2011 Jun;82(4):726-30.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N12135/15α-Hydroxy-20-oxo-6-7-seco-ent-kaur-16-en-1-7α-6-11α-diolide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N12135/
Clinical Information
No Development Reported
CAS Number
1355450-84-8
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