6-Hydroxywarfarin

6-Hydroxywarfarin is a metabolite of (+) -warfarin. 6-Hydroxywarfarin is a weaker vitamin K antagonist. 6-Hydroxywarfarin is metabolized by the cytochrome P450 isomer 2C9 (CYP2C9) [1].

Product Specifications

CAS Number

[17834-02-5]

Product Name Alternative

(S)-(+)-Abscisic acid; ABA

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Cytochrome P450

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6-hydroxywarfarin.html

Solubility

10 mM in DMSO

Smiles

O=C1OC2=CC=C(C=C2C(O)=C1C(CC(C)=O)C3=CC=CC=C3)O

Molecular Formula

C19H16O5

Molecular Weight

324.33

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hartman G, et al. The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening. Bioorg Med Chem Lett. 2024 Feb 28;102:129675.