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UCT943

UCT943 is a next-generation Plasmodium falciparum PI4K inhibitor. UCT943 inhibits the P. vivax PI4K (PvPI4K) enzyme with an IC50 of 23 nM[1].

Product Specifications

CAS Number

[1450666-80-4]

UNSPSC

12352005

Target

Parasite; PI4K

Type

Reference compound

Related Pathways

Anti-infection; PI3K/Akt/mTOR

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/UCT943.html

Purity

99.08

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

FC(F)(F)C1=CC=C(C2=NC(C3=CC=C(C(N4CCNCC4)=O)C=C3)=CN=C2N)C=C1

Molecular Formula

C22H20F3N5O

Molecular Weight

427.42

References & Citations

[1]Brunschwig C, et al. UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria. Antimicrob Agents Chemother. 2018 Aug 27;62 (9) . pii: e00012-18.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-112435/UCT943-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-112435/UCT943-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PI4K; Plasmodium

Available Sizes

Curated Selection

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