TRPC6-IN-3
Product Specifications
UNSPSC Description
TRPC6-IN-3 (compound 17) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. TRPC6-IN-3 modulates not only intracellular calcium concentration, but also membrane potential by modulating the flux of cations including calcium and sodium ions. TRPC6-IN-3 can be used in research of respiratory system[1].
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/trpc6-in-3.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(C2=NN=C(N)C=C2)CC1)C3=NC=C(OC4=CC=C(F)C=C4)C(OC)=C3
Molecular Weight
423.44
References & Citations
[1]Thierry B, et, al. Inhibitors of TRPC6 for treating respiratory conditions. WO2021209510.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148129/TRPC6-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148129/TRPC6-IN-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2311863-36-0
Available Sizes
Curated Selection
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