Chitohexaose (hexahydrochloride)
Product Specifications
UNSPSC Description
Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites of TLR4 and inhibits LPS induced inflammation[1][2].
Target Antigen
Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/chitohexaose-hexahydrochloride.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H](O[C@H]1O[C@@H]([C@@H]([C@H]2N)O)[C@H](O[C@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@@H](N)C=O)CO)[C@H]([C@@H]([C@H]1N)O)O[C@@H]([C@@H]([C@H]3O)N)O[C@@H]([C@H]3O[C@@H]([C@@H]([C@H]4O)N)O[C@@H]([C@H]4O[C@@H]([C@@H]([C@H]5O)N)O[C@@H]([C@H]5O)CO)CO)CO.Cl.Cl.Cl.Cl.Cl.Cl
Molecular Weight
1203.72
References & Citations
[1]Qini Zhao, et al. Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties. Oxid Med Cell Longev. 2020 Apr 11;2020:2394704.|[2]Santosh K Panda, et al. Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia. PLoS Pathog. 2012;8(5):e1002717.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7697C/Chitohexaose-hexahydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7697C/
Clinical Information
No Development Reported
CAS Number
127171-88-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
