Human IBSP Protein, His Tag

Description :Recombinant Human IBSP Protein with C-terminal 6XHis tag Background : The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. Molecular Characterization: mass of 34.3 kDa after removal of the signal peptide. The apparent molecular mass of IBSP-His is approximately 55-70 kDa due to glycosylation. Tag :C-6XHis Tag

Product Specifications

Product Name Alternative

BSP; BNSP; SP-II; BSP-II

UniProt

P21815

Host

HEK293

Target Antigen

IBSP

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.