Recombinant Human CLDN2 Protein, hFc Tag

Molecular Characterization: CLDN2?Ser29-Gln78?+hFc?Glu99-Ala330? Molecular Weight: The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of CLDN2-hFc is approximately 25-35 kDa due to glycosylation. Description: Recombinant human CLDN2 protein with C-terminal human Fc tag This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]

Product Specifications

Product Name Alternative

Claudin-2, SP82

UniProt

P57739

Host

HEK293

Target Antigen

CLDN2

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.