Recombinant Mouse DNAM-1 Protein, hFc Tag

Molecular Characterization: Mouse DNAM-1 (Glu19-Pro254) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 52.9 kDa after removal of the signal peptide. The apparent molecular mass of mDNAM-1-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse DNAM-1 protein with C-terminal human Fc tagInvolved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.[UniProtKB/Swiss-Prot Function]

Product Specifications

Product Name Alternative

CD226, PTA1

UniProt

Q5DW69

Host

HEK293

Target Antigen

DNAM-1

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.