Recombinant Human CB2 (1-33) Protein, hFc Tag

Molecular Characterization: CB2 (Met1-Lys33) hFc (Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 29.8 kDa after removal of the signal peptide.The apparent molecular mass of CB2-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human CB2 Protein with C-terminal human Fc tagThe cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein) -coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.