Batroxobin
Source:nullPhysical Appearance:Sterile Filtered white lyophilized powder.Biological ActivitynullBatroxobin is a serin protease that reduces fibronogen levels and is originally extracted from snake venom of Bothrops Atrox. Batroxobin is used in defibrinogenation and thrombolysis and also has an effect on c-fos gene and growth factor.Batroxobin can efficiently restrain proliferation of VSMCs, by blocking the release and uptake of Ca2+, thus influencing [Ca2+]i.Batroxobin converts fibrinogen to fibrin through the restricted release of fibrinopeptide-A from fibrinogen to promote blood to clot. Unlike thrombin, it is not affected by heparin and hirudin.Batroxobin, isolated from Bothrops atrox snake venom, has an Mw of approximately 43kDa.
Product Specifications
Product Name Alternative
Thrombin-like enzyme batroxobin, EC 3.4.21.74, BX, Bothrops atrox serine proteinase, Venombin-A, Batroxobin.
Purification
Null
Format
The Batroxobin protein was lyophilized from a concentrated (1mg/mL) solution with no additives.
Storage Conditions
Store the lyophilized Batroxobin between 2-8°C. Do not freeze!
Applications Notes
It is recommended to reconstitute the lyophilized Batroxobin in sterile 18MO-cm H2O not less than 100μg/ml or more than 10mg/ml solutions.
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