IGF2 Mouse

Source:Escherichia Coli.Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.Biological ActivityThe ED50 as determined by FDC-P1 cell proliferation is = 50 ng/mL, corresponding to a specific activity of = 2.0 x 10^4 units/mg.Insulin-like growth factor II (IGF-II) is an important foetal growth hormone.IGF-II is made by theca cells during gestation. IGF-II binds the sink IGF-II receptor (IGF2R) which results in IGF-II degradation.IGF-II also engages the IGF-I receptor (IGF1R) to arbitrate embryonic growth.IGF2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, monomeric polypeptide chain containing 67 amino acids and having a total molecular mass of 7.4kDa.The IGF2 is purified by proprietary chromatographic techniques.

Product Specifications

Product Name Alternative

Somatomedin-A, IGF2, INSIGF, pp9974, C11orf43, FLJ22066, FLJ44734

Purification

Greater than 95.0% as determined by SDS-PAGE.

Format

Lyophilized from a sterile (0.2μ) filtered solution containing 0.1 % trifluoroacetic acid (TFA) .

Storage Conditions

Lyophilized IGF2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGF2 Human should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.

Applications Notes

It is recommended to reconstitute the lyophilized IGF2 in sterile water at a concentration of 0.1 mg/ml, which can then be further diluted to other aqueous solutions.