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Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide D1

Source : Sf9 insect cells. SNRPD1 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 14,306 Dalton. SNRPD1 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques. SNRPD1 is a small nuclear ribonucleoprotein which is a member of the SNRNP core protein family. SNRPD1 may act as a charged protein scaffold to stimulate SNRNP assembly or strengthen SNRNP-SNRNP interactions via nonspecific electrostatic contacts with RNA. In the autoimmune disease systemic lupus erythematosus, antinuclear antibodies are developed with Sm specificity.

Product Specifications

Product Name Alternative

Small nuclear ribonucleoprotein Sm D1||Sm-D1||Sm-D autoantigen||snRNP core protein D1||SNRPD1||SMD1||SNRPD||HsT2456.

Purification

Greater than 80% as determined by SDS-PAGE.

Components

Concentration 0.1 mg/mL in sterile PBS

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

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