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Pomalidomide-PEG4-C-COOH

Product Specifications

UNSPSC Description

Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/14-__2-_2,6-dioxopiperidin-3-yl_-1,3-dioxoisoindolin-4-yl_amino_-3,6,9,12-tetraoxatetradecan-1-oic_acid.html

Purity

99.10

Solubility

DMSO : 50 mg/mL (ultrasonic)|Ethanol : 25 mg/mL (ultrasonic)

Smiles

O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3NCCOCCOCCOCCOCC(O)=O

Molecular Weight

507.49

References & Citations

[1]Guangrong Zheng, et al. Compounds that induce degradation of anti-apoptotic bcl-2 family proteins and the uses thereof. WO2017184995A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-21930/Pomalidomide-PEG4-C-COOH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-21930/Pomalidomide-PEG4-C-COOH-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2097938-44-6

Available Sizes

Curated Selection

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