PRTN3 Native Protein
Source : Native. PRTN3 is a natural antigen having a molecular mass of 25kDa to 32kDa due to glycosylation isoforms. PRTN3 is isolated from human peripheral blood leukocytes. PRTN3 is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema once managed by tracheal insufflation to hamsters.
Product Specifications
Product Name Alternative
AGP7||P29||PR-3||ACPA||C-ANCA||MBT||MBN||Leukocyte proteinase 3||Neutrophil proteinase 4||Wegener granulomatosis autoantigen||Azurophil granule protein 7||myeloblastin||Serine proteinase neutrophil.
Purification
Greater than 80% in the sum of different glycosylation isoforms according to following section as determined by SDS-PAGE and capillary electrophoresis.
Components
PRTN3 is supplied in 16mM HEPES buffer pH-8.0, 400mM NaCl, and 20% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
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