GLP 2

Source : Glucagon Like Peptide-2 contains 34 amino acids having a molecular mass of 3922.38 Dalton. GLP-2 functions as an intestinal growth factor, which stimulates intestinal epithelial growth. GLP2 is involved in diabetes-associated bowel growth. GLP2 enhances cell differentiation, playing a role as a cytokine and in tissue regeneration, and mediating cytoprotection. GLP2 is invloded numerous therapeutic applications. GLP2 regulates signaling pathways coupled to cell proliferation and cell death by apoptosis.GLP-2 is produced by specific post-translational proteolytic cleavage of proglucagon GLP-2 is manufactured by the intestinal endocrine L cell and by several neurons in the central nervous system.

Product Specifications

Product Name Alternative

GLP2||GLP-2||Glucagon Like Peptide-2.

Purification

Greater than 95.0% as determined by RP-HPLC.

Components

The protein (1mg/mL) was lyophilized with no additives.

Storage Conditions

Lyophilized GLP2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GLP2 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

Applications Notes

It is recommended to reconstitute the lyophilized GLP-2 in sterile 18MΩ-cm H2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.